Abstract
Secondary changes in regional cerebral blood flow (rCBF) have been observed to occur within hours to days in acute focal cerebral ischemia. Following experimental occlusion of the middle cerebral artery (MCA) the secondary decline in rCBF during the first 4 hours of ischemia appeared to correlate with progressive brain swelling (Hossmann and Schuier, 1980). In subsequent studies the delayed rise in intracortical vascular resistance as the cause of the decrease in rCBF was noted (Shima et al, 1983). It is assumed that the continuing failure of cerebral hemodynamics associated with the delayed rise in regional cerebral vascular resistance (rCVR) can aggravate the ischemia and in this way can contribute to the extension of cerebral infarction.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
