Changes in noradrenaline sensitivity and morphology of arterial resistance vessels during development of high blood pressure in spontaneously hypertensive rats.

Abstract

HomeHypertensionVol. 2, No. 5Changes in noradrenaline sensitivity and morphology of arterial resistance vessels during development of high blood pressure in spontaneously hypertensive rats. Free AccessAbstractPDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessAbstractPDF/EPUBChanges in noradrenaline sensitivity and morphology of arterial resistance vessels during development of high blood pressure in spontaneously hypertensive rats. M J Mulvany, C Aalkjaer and J Christensen M J MulvanyM J Mulvany Search for more papers by this author , C AalkjaerC Aalkjaer Search for more papers by this author and J ChristensenJ Christensen Search for more papers by this author Originally published1 Sep 1980https://doi.org/10.1161/01.HYP.2.5.664Hypertension. 1980;2:664–671 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Cheung C, Biousse V, Keane P, Schiffrin E and Wong T (2022) Hypertensive eye disease, Nature Reviews Disease Primers, 10.1038/s41572-022-00342-0, 8:1, Online publication date: 1-Dec-2022. Aalkjær C, Nilsson H and De Mey J (2021) Sympathetic and sensory-motor nerves in peripheral small arteries, Physiological Reviews, 10.1152/physrev.00007.2020, 101:2, (495-544), Online publication date: 1-Apr-2021. Li Y, Wang Q, Muir E, Kiel J and Duong T (2020) Retinal Vascular and Anatomical Features in the Spontaneously Hypertensive Rat, Current Eye Research, 10.1080/02713683.2020.1752738, 45:11, (1422-1429), Online publication date: 1-Nov-2020. Stannov S, Brasen J, Salomonsson M, Holstein‐Rathlou N and Sorensen C (2019) Interactions between renal vascular resistance and endothelium‐derived hyperpolarization in hypertensive rats in vivo, Physiological Reports, 10.14814/phy2.14168, 7:15, Online publication date: 1-Aug-2019. Hirunpattarasilp C, Attwell D and Freitas F (2019) The role of pericytes in brain disorders: from the periphery to the brain, Journal of Neurochemistry, 10.1111/jnc.14725, 150:6, (648-665), Online publication date: 1-Sep-2019. Komatsu S, Kitazawa T and Ikebe M (2017) Visualization of stimulus‐specific heterogeneous activation of individual vascular smooth muscle cells in aortic tissues, Journal of Cellular Physiology, 10.1002/jcp.25903, 233:1, (434-446), Online publication date: 1-Jan-2018. Rizzoni D, Agabiti-Rosei C and Agabiti-Rosei E (2017) Hemodynamic Consequences of Changes in Microvascular Structure, American Journal of Hypertension, 10.1093/ajh/hpx032, 30:10, (939-946), Online publication date: 1-Oct-2017., Online publication date: 1-Oct-2017. Simões L, Conceição-Filho G, Ribeiro T, Jesus A, Fregoneze J, Silva A, Petreanu M, Cechinel-Filho V, Niero R, Niero H, Tamanaha M and Silva D (2016) Evidences of antihypertensive potential of extract from Solanum capsicoides All. in spontaneously hypertensive rats, Phytomedicine, 10.1016/j.phymed.2016.02.020, 23:5, (498-508), Online publication date: 1-May-2016. Khammy M, Angus J and Wright C (2016) Vascular reactivity of rabbit isolated renal and femoral resistance arteries in renal wrap hypertension, European Journal of Pharmacology, 10.1016/j.ejphar.2016.01.004, 773, (32-41), Online publication date: 1-Feb-2016. Bouzinova E, Wiborg O, Aalkjaer C and Matchkov V (2015) Role of Peripheral Vascular Resistance for the Association Between Major Depression and Cardiovascular Disease, Journal of Cardiovascular Pharmacology, 10.1097/FJC.0000000000000187, 65:4, (299-307), Online publication date: 1-Apr-2015. Li Y, Shen Q, Huang S, Li W, Muir E, Long J and Duong T (2015) Cerebral angiography, blood flow and vascular reactivity in progressive hypertension, NeuroImage, 10.1016/j.neuroimage.2015.02.053, 111, (329-337), Online publication date: 1-May-2015. MIDOH N, MIYAZAWA N and EGUCHI F (2014) Effects of a Hot-Water Extract of Porcini ( Boletus aestivalis ) Mushrooms on the Blood Pressure and Heart Rate of Spontaneously Hypertensive Rats , Bioscience, Biotechnology, and Biochemistry, 10.1271/bbb.130085, 77:8, (1769-1772), Online publication date: 23-Aug-2013. Pires P, Dams Ramos C, Matin N and Dorrance A (2013) The effects of hypertension on the cerebral circulation, American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.00490.2012, 304:12, (H1598-H1614), Online publication date: 15-Jun-2013. Bouzinova E, Møller-Nielsen N, Boedtkjer D, Broegger T, Wiborg O, Aalkjaer C and Matchkov V (2012) Chronic Mild Stress–Induced Depression-Like Symptoms in Rats and Abnormalities in Catecholamine Uptake in Small Arteries, Psychosomatic Medicine, 10.1097/PSY.0b013e31824c40a9, 74:3, (278-287), Online publication date: 1-Apr-2012. Hughes R, Angus J, Winkel K and Wright C (2012) A pharmacological investigation of the venom extract of the Australian box jellyfish, Chironex fleckeri, in cardiac and vascular tissues, Toxicology Letters, 10.1016/j.toxlet.2011.11.025, 209:1, (11-20), Online publication date: 1-Feb-2012. Sánchez D, Kassan M, Contreras M, Carrón R, Recio I, Montero M and Sevilla M (2011) Long-term intake of a milk casein hydrolysate attenuates the development of hypertension and involves cardiovascular benefits, Pharmacological Research, 10.1016/j.phrs.2011.01.015, 63:5, (398-404), Online publication date: 1-May-2011. Pradhan R and Chakravarthy V (2010) Informational dynamics of vasomotion in microvascular networks: a review, Acta Physiologica, 10.1111/j.1748-1716.2010.02198.x, 201:2, (193-218), Online publication date: 1-Feb-2011. Luksha L, Poston L, Gustafsson J, Aghajanova L and Kublickiene K (2005) Gender-Specific Alteration of Adrenergic Responses in Small Femoral Arteries From Estrogen Receptor-β Knockout Mice, Hypertension, 46:5, (1163-1168), Online publication date: 1-Nov-2005. Matchkov V, Rahman A, Peng H, Nilsson H and Aalkjaer C (2009) Junctional and nonjunctional effects of heptanol and glycyrrhetinic acid derivates in rat mesenteric small arteries, British Journal of Pharmacology, 10.1038/sj.bjp.0705870, 142:6, (961-972), Online publication date: 1-Jul-2004. Sofola O, Knill A, Myers D, Hainsworth R and Drinkhill M (2004) High-salt diet and responses of the pressurized mesenteric artery of the dog to noradrenaline and acetylcholine, Clinical and Experimental Pharmacology and Physiology, 10.1111/j.1440-1681.2004.04069.x, 31:10, (696-699), Online publication date: 1-Oct-2004. Balt J, Mathy M, Pfaffendorf M and Zwieten P (2003) Sympatho-inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar-Kyoto rats, Fundamental and Clinical Pharmacology, 10.1046/j.1472-8206.2003.00147.x, 17:1, (83-91), Online publication date: 1-Feb-2003. Brandin L, Bergstr??m G, Manhem K and Gustafsson H (2003) Oestrogen modulates vascular adrenergic reactivity of the spontaneously hypertensive rat, Journal of Hypertension, 10.1097/00004872-200309000-00019, 21:9, (1695-1702), Online publication date: 1-Sep-2003. Wells I and Blotcky A (2001) Coexisting independent sodium-sensitive and sodium-insensitive mechanisms of genetic hypertension in spontaneously hypertensive rats (SHR), Canadian Journal of Physiology and Pharmacology, 10.1139/y01-061, 79:9, (779-784), Online publication date: 1-Sep-2001. Vázquez-Pérez S, Navarro-Cid J, Heras N, Cediel E, Sanz-Rosa D, Ruilope L, Cachofeiro V and Lahera V (2001) Relevance of endothelium-derived hyperpolarizing factor in the effects of hypertension on rat coronary relaxations, Journal of Hypertension, 10.1097/00004872-200103001-00004, 19:Supplement, (539-545), Online publication date: 1-Mar-2001. Rizzoni D, Rodella L, Porteri E, Rezzani R, Guelfi D, Piccoli A, Castellano M, Muiesan M, Bianchi R and Rosei E (2000) Time course of apoptosis in small resistance arteries of spontaneously hypertensive rats, Journal of Hypertension, 10.1097/00004872-200018070-00010, 18:7, (885-891), Online publication date: 1-Jul-2000. Zicha J and Kuneš J (1999) Ontogenetic Aspects of Hypertension Development: Analysis in the Rat, Physiological Reviews, 10.1152/physrev.1999.79.4.1227, 79:4, (1227-1282), Online publication date: 10-Jan-1999. Van Zwieten P (2009) Diabetes and Hypertension: Experimental Models for Pharmacological Studies, Clinical and Experimental Hypertension, 10.3109/10641969909068644, 21:1-2, (1-16), Online publication date: 1-Jan-1999. Arribas S, Costa R, Salomone S, Morel N, Godfraind T and McGrath J (2016) Functional Reduction and Associated Cellular Rearrangement in SHRSP Rat Basilar Arteries Are Affected by Salt Load and Calcium Antagonist Treatment, Journal of Cerebral Blood Flow & Metabolism, 10.1097/00004647-199905000-00006, 19:5, (517-527), Online publication date: 1-May-1999. Malpas S, Hore T, Navakatikyan M, Lukoshkova E, Nguang S and Austin P (1999) Resonance in the renal vasculature evoked by activation of the sympathetic nerves, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 10.1152/ajpregu.1999.276.5.R1311, 276:5, (R1311-R1319), Online publication date: 1-May-1999. Davie C, Everitt D and Standen N (1999) Increase in the vasorelaxant potency of KATP channel opening drugs by adenosine A1 and A2 receptors in the pig coronary artery, European Journal of Pharmacology, 10.1016/S0014-2999(99)00635-4, 383:2, (155-162), Online publication date: 1-Oct-1999. Fronhoffs S, Mengden T, Oliveira J, Sachinidis A and Vetter H (1999) Cholesterol enhances contractile responses in isolated small mesenteric arteries of normotensive and spontaneously hypertensive rats, Journal of Hypertension, 10.1097/00004872-199917121-00025, 17:Supplement, (1941-1947), Online publication date: 1-Dec-1999. Davie C and Standen N (1998) Enhancement of the vasorelaxant potency of nicorandil by metabolic inhibition and adenosine in the pig coronary artery, Cardiovascular Research, 10.1016/S0008-6363(97)00262-9, 37:3, (791-798), Online publication date: 1-Mar-1998., Online publication date: 1-Mar-1998. Adegunloye B and Sofola O (1998) Relaxation responses of aortic rings from salt-loaded high calcium fed rats to potassium chloride, calcium chloride and magnesium sulphate, Pathophysiology, 10.1016/S0928-4680(97)10004-9, 4:4, (275-280), Online publication date: 1-Jan-1998. Malpas S, Evans R, Head G and Lukoshkova E (1998) Contribution of renal nerves to renal blood flow variability during hemorrhage, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 10.1152/ajpregu.1998.274.5.R1283, 274:5, (R1283-R1294), Online publication date: 1-May-1998. Davie C, Kubo M and Standen N (2009) Potassium channel activation and relaxation by nicorandil in rat small mesenteric arteries, British Journal of Pharmacology, 10.1038/sj.bjp.0702232, 125:8, (1715-1725), Online publication date: 1-Dec-1998. Dickhout J and Lee R (1997) Structural and Functional Analysis of Small Arteries From Young Spontaneously Hypertensive Rats, Hypertension, 29:3, (781-789), Online publication date: 1-Mar-1997.Shaw L, Ohanian J and Heagerty A (1997) Calcium Sensitivity and Agonist-Induced Calcium Sensitization in Small Arteries of Young and Adult Spontaneously Hypertensive Rats, Hypertension, 30:3, (442-448), Online publication date: 1-Sep-1997. Laurant P, Touyz R and Schiffrin E (1997) Effect of magnesium on vascular tone and reactivity in pressurized mesenteric resistance arteries from spontaneously hypertensive rats, Canadian Journal of Physiology and Pharmacology, 10.1139/y97-044, 75:4, (293-300), Online publication date: 1-Apr-1997. Arribas S, Gordon J, Daly C, Dominiczak A and McGrath J (1996) Confocal Microscopic Characterization of a Lesion in a Cerebral Vessel of the Stroke-Prone Spontaneously Hypertensive Rat, Stroke, 27:6, (1118-1123), Online publication date: 1-Jun-1996. Sekiguchi F, Adachi T, Matsubara H, Matsuda K, Kita K, Shimamura K and Sunano S (1996) SPONTANEOUS AND AGONIST-INDUCED CONTRACTIONS AND ENDOTHELIUM-DEPENDENT RELAXATION IN AORTAE FROM SHRSP AND WKY RATS UNDER VARIOUS LEVELS OF PASSIVE FORCE, Clinical and Experimental Pharmacology and Physiology, 10.1111/j.1440-1681.1996.tb02765.x, 23:6-7, (483-489), Online publication date: 1-Jul-1996. Kam K, Hendriks M, Pijl A, van Marle J, van Veen H, Pfaffendorf M and van Zwieten P (1996) Contractile Responses to Various Stimuli in Isolated Resistance Vessels from Simultaneously Hypertensive and Streptozotocin-Diabetic Rats, Journal of Cardiovascular Pharmacology, 10.1097/00005344-199601000-00026, 27:1, (167-175), Online publication date: 1-Jan-1996. Ito M, Soma M, Izumi Y and Kanmatsuse K (1995) Effects of long-term treatment with angiotensin-converting enzyme inhibitor on angiotensin II and prostacyclin release from mesenteric arteries in spontaneously hypertensive rats, Prostaglandins, Leukotrienes and Essential Fatty Acids, 10.1016/0952-3278(95)90057-8, 53:5, (359-363), Online publication date: 1-Nov-1995. Deschepper C, Li J, Schiffrin E and Welner S (1994) Hypertension induced by brain grafts from fetal spontaneously hypertensive rats., Hypertension, 23:6_pt_1, (765-773), Online publication date: 1-Jun-1994.Rizzoni D, Castellano M, Porteri E, Bettoni G, Muiesan M and Agabiti Rosei E (1994) Delayed development of hypertension after short-term nitrendipine treatment., Hypertension, 24:1, (131-139), Online publication date: 1-Jul-1994.Falloon B and Heagerty A (1994) In vitro perfusion studies of human resistance artery function in essential hypertension., Hypertension, 24:1, (16-23), Online publication date: 1-Jul-1994. Boels P, Arner A, Malmqvist U and Uvelius B (1994) Structure and mechanics of growing arterial microvessels from hypertrophied urinary bladder in the rat, Pfl�gers Archiv European Journal of Physiology, 10.1007/BF00378528, 426:6, (506-515), Online publication date: 1-Apr-1994. Stephens N and Heagerty A (2016) The Sympathetic Nervous System and Small Artery Neuroeffector Function in Hypertension, Vascular Medicine Review, 10.1177/1358863X9400500107, vmr-5:1, (73-91), Online publication date: 1-Feb-1994. Byg A, Bund S, Mulvany M and Aalkjær C (1994) THE EFFECT OF COCAINE AND DESIPRAMINE ON NEURONAL UPTAKE OF [ 3 H]-NORADRENALINE AND SENSITIVITY TO NORADRENALINE OF RAT MESENTERIC RESISTANCE ARTERIES , Clinical and Experimental Pharmacology and Physiology, 10.1111/j.1440-1681.1994.tb02563.x, 21:8, (623-630), Online publication date: 1-Aug-1994. GUSTAFSSON H, BÜLOW A and NILSSON H (1994) Rhythmic contractions of isolated, pressurized small arteries from rat, Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1994.tb09794.x, 152:2, (145-152), Online publication date: 1-Oct-1994. Falloon B, Bund S, Tulip J and Heagerty A (1993) In vitro perfusion studies of resistance artery function in genetic hypertension., Hypertension, 22:4, (486-495), Online publication date: 1-Oct-1993.Ohanian J, Izzard A, Littlewood M and Heagerty A (1993) Regulation of diacylglycerol metabolism by vasoconstrictor hormones in intact small arteries., Circulation Research, 72:6, (1163-1171), Online publication date: 1-Jun-1993. GUSTAFSSON H, MULVANY M and NILSSON H (1993) Rhythmic contractions of isolated small arteries from rat: influence of the endothelium, Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1993.tb09545.x, 148:2, (153-163), Online publication date: 1-Jun-1993. Ledingham J and Millar J (1993) STEREOLOGICAL STUDIES ON MESENTERIC RESISTANCE ARTERY STRUCTURE IN NEW ZEALAND GENETICALLY HYPERTENSIVE AND CONTROL RATS, Clinical and Experimental Pharmacology and Physiology, 10.1111/j.1440-1681.1993.tb01705.x, 20:5, (359-361), Online publication date: 1-May-1993. Heagerty A, Aalkjaer C, Bund S, Korsgaard N and Mulvany M (1993) Small artery structure in hypertension. Dual processes of remodeling and growth., Hypertension, 21:4, (391-397), Online publication date: 1-Apr-1993. Marín J (1993) Mechanisms involved in the increased vascular resistance in hypertension, Journal of Autonomic Pharmacology, 10.1111/j.1474-8673.1993.tb00264.x, 13:2, (127-176), Online publication date: 1-Apr-1993. Laneuville O, Couture R and Pace-Asciak C (2012) Hepoxilins sensitize blood vessels to noradrenaline-stereospecificity of action, British Journal of Pharmacology, 10.1111/j.1476-5381.1992.tb14249.x, 105:2, (297-304), Online publication date: 1-Feb-1992. Kashimoto S, Nonaka A, Nakamura T, Yamaguchi T and Kumazawa T (1992) Cardiac and hepatic metabolism in spontaneously hypertensive rats following acute blood loss, Journal of Anesthesia, 10.1007/s0054020060284, 6:3, (284-288), Online publication date: 1-Jul-1992. Ludwig J, Gerlich M, Halbrügge T and Graefe K (1991) Plasma norepinephrine and dihydroxyphenylglycol in essential hypertension., Hypertension, 17:4, (546-552), Online publication date: 1-Apr-1991.Stephens N, Bund S, Jagger C and Heagerty A (1991) Arterial neuroeffector responses in early and mature spontaneously hypertensive rats., Hypertension, 18:5, (674-682), Online publication date: 1-Nov-1991.Bund S, West K and Heagerty A (1991) Effects of protection from pressure on resistance artery morphology and reactivity in spontaneously hypertensive and Wistar-Kyoto rats., Circulation Research, 68:5, (1230-1240), Online publication date: 1-May-1991.Griffin S, Brown W, MacPherson F, McGrath J, Wilson V, Korsgaard N, Mulvany M and Lever A (1991) Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism., Hypertension, 17:5, (626-635), Online publication date: 1-May-1991. Mulvany M (1991) Structure and Function of Resistance Vessels in Hypertension Cellular Aspects of Hypertension, 10.1007/978-3-662-00983-3_1, (3-11), . Vila E, Macrae I and Reid J (2012) Differences in inositol phosphate production in blood vessels of normotensive and spontaneously hypertensive rats, British Journal of Pharmacology, 10.1111/j.1476-5381.1991.tb12425.x, 104:2, (296-300), Online publication date: 1-Oct-1991. Matias A, Albino-Teixeira A, Polónia J and Azevedo I (1991) Long-term administration of 1,3-dipropyl-8-sulfophenylxanthine causes arterial hypertension, European Journal of Pharmacology, 10.1016/0014-2999(91)90206-6, 193:1, (101-104), Online publication date: 1-Jan-1991. Tabrizchi R and Triggle C (1991) Influence of Nω-nitro-L-arginine methyl on pressor responses elicited by sympathetic nerve stimulation in pithed normotensive and hypertensive rats, Life Sciences, 10.1016/0024-3205(91)90641-N, 49:26, (1989-1995), Online publication date: 1-Jan-1991. Socorro L, Vallega G, Nunn A, Moore T and Canessa M (1990) Vascular smooth muscle cells from the Milan hypertensive rat exhibit decreased functional angiotensin II receptors., Hypertension, 15:6_pt_1, (591-599), Online publication date: 1-Jun-1990.Bukoski R, Wang D and Wagman D (1990) Injection of 1,25-(OH)2 vitamin D3 enhances resistance artery contractile properties., Hypertension, 16:5, (523-531), Online publication date: 1-Nov-1990. Mulvany M (1989) Vascular Mechanisms in Development and Maintenance of Hypertension in Spontaneously Hypertensive Rats Essential Hypertension 2, 10.1007/978-4-431-68090-1_19, (239-250), . Huzoor-Akbar , Chen N, Fossen D and Wallace D (1989) Increased vascular contractile sensitivity to serotonin in spontaneously hypertensive is linked with increased turnover of phosphoinositide, Life Sciences, 10.1016/0024-3205(89)90042-8, 45:7, (577-583), Online publication date: 1-Jan-1989. Nyborg N and Bevan J (1988) Increased alpha-adrenergic receptor affinity in resistance vessels from hypertensive rats., Hypertension, 11:6_pt_2, (635-638), Online publication date: 1-Jun-1988. Borkowski K (1988) Pre- and postjunctional β-adrenoreceptors and hypertension, Journal of Autonomic Pharmacology, 10.1111/j.1474-8673.1988.tb00179.x, 8:2, (153-171), Online publication date: 1-Jun-1988. Pipili E, Zoumboulis G and Maragoudakis M (1988) Prostaglandin I 2 and thromboxane A 2 production in relation to α 1 and α 2 -adrenoreceptor activation in the normotensive and hypertensive rat , Journal of Autonomic Pharmacology, 10.1111/j.1474-8673.1988.tb00577.x, 8:4, (333-342), Online publication date: 1-Dec-1988. Lin A, Lue H, Lin R, Wang Y, Pan C, Kuo J and Chai C (1988) Paramedian reticular nucleus—Sympathetic inhibition in spontaneously hypertensive rats, Brain Research Bulletin, 10.1016/0361-9230(88)90205-5, 21:4, (651-657), Online publication date: 1-Oct-1988. Longhurst P, Rice P, Taylor D and Fleming W (1988) Sensitivity of caudal arteries and the mesenteric vascular bed to norepinephrine in DOCA-salt hypertension., Hypertension, 12:2, (133-142), Online publication date: 1-Aug-1988. Heagerty A, Izzard A, Ollerenshaw J and Bund S (1988) Blood vessels and human essential hypertension, International Journal of Cardiology, 10.1016/0167-5273(88)90312-9, 20:1, (15-28), Online publication date: 1-Jul-1988. Soltis E and Bohr D (1987) Vascular reactivity in the spontaneously hypertensive stroke-prone rat. Effect of antihypertensive treatment., Hypertension, 9:5, (492-497), Online publication date: 1-May-1987.Aalkjaer C, Heagerty A, Bailey I, Mulvany M and Swales J (1987) Studies of isolated resistance vessels from offspring of essential hypertensive patients., Hypertension, 9:6_pt_2, (III155), Online publication date: 1-Jun-1987.Aalkjaer C, Heagerty A, Petersen K, Swales J and Mulvany M (1987) Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation--contraction coupling in isolated resistance vessels from essential hypertensives., Circulation Research, 61:2, (181-186), Online publication date: 1-Aug-1987. Johns A, Leijten P, Yamamoto H, Hwang K and van Breemen C (1987) Calcium regulation in vascular smooth muscle contractility, The American Journal of Cardiology, 10.1016/0002-9149(87)90171-8, 59:2, (A18-A23), Online publication date: 1-Jan-1987. Bruner C, Myers J, Sing C, Jokelainen P and Webb R (1986) Genetic association of hypertension and vascular changes in stroke-prone spontaneously hypertensive rats., Hypertension, 8:10, (904-910), Online publication date: 1-Oct-1986.Loeb A and Bean B (1986) Antihypertensive drugs inhibit hypertension-associated aortic DNA synthesis in the rat., Hypertension, 8:12, (1135-1142), Online publication date: 1-Dec-1986. Aoki K (1986) Calcium Membrane Theory of Essential Hypertension Essential Hypertension, 10.1007/978-4-431-68048-2_21, (223-242), . KAPOCSI J and VIZI E (1986) MODULATION OF 3H-NORADRENALINE RELEASE FROM ISOLATED HUMAN CYSTIC ARTERY Receptors and Centrally Acting Drugs Pharmacokinetics and Drug Metabolism, 10.1016/B978-0-08-034191-0.50018-0, (99-104), . Heagerty A, Ollerenshaw J and Swales J (2012) Abnormal vascular phosphoinositide hydrolysis in the spontaneously hypertensive rat, British Journal of Pharmacology, 10.1111/j.1476-5381.1986.tb11185.x, 89:4, (803-807), Online publication date: 1-Dec-1986. HOLSTEIN-RATHLOU N and LEYSSAC P (1986) TGF-mediated oscillations in the proximal intratubular pressure: differences between spontaneously hypertensive rats and Wistar-Kyoto rats, Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1986.tb07824.x, 126:3, (333-339), Online publication date: 1-Mar-1986. Mulvany M (1986) Altered Vascular Calcium Metabolism As a Possible Cause of Increased Blood Pressure in Essential Hypertension Essential Hypertension, 10.1007/978-4-431-68048-2_5, (51-65), . Sadoshima S, Fujishima M, Yoshida F, Ibayashi S, Shiokawa O and Omae T (2018) Cerebral autoregulation in young spontaneously hypertensive rats. Effect of sympathetic denervation., Hypertension, 7:3_pt_1, (392-397), Online publication date: 1-May-1985.Jespersen L, Nyborg N, Pedersen O, Mikkelsen E and Mulvany M (1985) Cardiac mass and peripheral vascular structure in hydralazine-treated spontaneously hypertensive rats., Hypertension, 7:5, (734-741), Online publication date: 1-Sep-1985.Sadoshima S, Yoshida F, Ibayashi S, Shiokawa O and Fujishima M (1985) Upper limit of cerebral autoregulation during development of hypertension in spontaneously hypertensive rats--effect of sympathetic denervation., Stroke, 16:3, (477-481), Online publication date: 1-May-1985. Aalkjaer C, Johannesen P, Pedersen E, Rasmussen A and Mulvany M (2009) RESISTANCE VESSEL ABNORMALITIES IN PREECLAMPSIA., Acta Medica Scandinavica, 10.1111/j.0954-6820.1985.tb08771.x, 217:S693, (23-27) NILSSON H, SJÖBLOM N and FOLKOW B (1985) Interaction between prejunctional α 2 -receptors and neuronal transmitter reuptake in small mesenteric arteries from the rat , Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1985.tb07713.x, 125:2, (245-252), Online publication date: 1-Oct-1985. St-Louis J and Massicotte G (1985) Chronic decrease of blood pressure by rat relaxin in spontaneously hypertensive rats, Life Sciences, 10.1016/0024-3205(85)90251-6, 37:14, (1351-1357), Online publication date: 1-Oct-1985. Schiffrin E, Thomé F and Genest J (1984) Vascular angiotensin II receptors in SHR., Hypertension, 6:5, (682-688), Online publication date: 1-Sep-1984.Roy J and Mayrovitz H (1984) Microvascular pressure, flow, and resistance in spontaneously hypertensive rats., Hypertension, 6:6_pt_1, (877-886), Online publication date: 1-Nov-1984. Gray S (2009) Spontaneous Hypertension in the Neonatal Rat. A Review, Clinical and Experimental Hypertension. Part A: Theory and Practice, 10.3109/10641968409044037, 6:4, (755-781), Online publication date: 1-Jan-1984. Soltis E and Field F (2009) Effect of High Blood Pressure Stress on Vascular Adrenergic Responsiveness in the Spontaneously Hypertensive Rat, Clinical and Experimental Hypertension. Part A: Theory and Practice, 10.3109/10641968409039594, 6:7, (1237-1255), Online publication date: 1-Jan-1984. Wennberg E, Hagberg H and Haljamäe H (1984) The Response of the Awake Spontaneously Hypertensive Rat (SHR) to Acute Blood Loss, Acta Anaesthesiologica Scandinavica, 10.1111/j.1399-6576.1984.tb02098.x, 28:4, (457-461), Online publication date: 1-Aug-1984. Bohr D and Webb R (1984) Vascular Smooth Muscle Function and Its Changes in Hypertension, The American Journal of Medicine, 10.1016/S0002-9343(84)80032-7, 77:4, (3-16), Online publication date: 1-Oct-1984. Gattone V, Evan A, Willis L and Luft F (1983) Renal afferent arteriole in the spontaneously hypertensive rat., Hypertension, 5:1, (8-16), Online publication date: 1-Jan-1983.Winquist R and Bohr D (1983) Structural and functional changes in cerebral arteries from spontaneously hypertensive rats., Hypertension, 5:3, (292-297), Online publication date: 1-May-1983.Mueller S (1983) Longitudinal study of the hindquarter vasculature during development in spontaneously hypertensive and Dahl salt-sensitive rats., Hypertension, 5:4, (489-497), Online publication date: 1-Jul-1983.Zimmerman B (1983) Peripheral neurogenic factors in acute and chronic alterations of arterial pressure., Circulation Research, 53:2, (121-130), Online publication date: 1-Aug-1983. Thorén P, Göthberg G, Lundin S, Nilsson H and Folkow B (1984) Some Aspects of Cardiovascular Nervous Control in Spontaneously Hypertensive Rats: Central and Peripheral Mechanisms Topics in Pathophysiology of Hypertension, 10.1007/978-94-009-6741-0_28, (321-333), . Mulvany M, Mikkelsen E, Pedersen O, Nyborg N and Jespersen L (1983) Cardiovascular abnormalities in spontaneously hypertensive rats. Causes or consequences of the increased blood pressure? Cardiac Adaptation to Hemodynamic Overload, Training and Stress, 10.1007/978-3-642-85326-5_34, (253-257), . (2012) POSTER COMMUNICATIONS, British Journal of Pharmacology, 10.1111/j.1476-5381.1983.tb16591.x, 80:S2, (650P-719P), Online publication date: 1-Dec-1983. Cauvin C and Pegram B (2009) Decreased Relaxation of Isolated Mesenteric Resistance Vessels from 2-Kidney, 1 Clip Goldblatt Hypertensive Rats, Clinical and Experimental Hypertension. Part A: Theory and Practice, 10.3109/10641968309069496, 5:3, (383-400), Online publication date: 1-Jan-1983. Mulvany M, Aalkjaer C, Nilsson H and Petersen T (1984) Evidence against Raised Intracellular Sodium Causing Myogenic Contraction in Rat Resistance Vessels Topics in Pathophysiology of Hypertension, 10.1007/978-94-009-6741-0_18, (212-222), . Olivetti G, Melissari M, Marchetti G and Anversa P (1982) Quantitative structural changes of the rat thoracic aorta in early spontaneous hypertension. Tissue composition, and hypertrophy and hyperplasia of smooth muscle cells., Circulation Research, 51:1, (19-26), Online publication date: 1-Jul-1982.Mulvany M, Nilsson H, Flatman J and Korsgaard N (1982) Potentiating and depressive effects of ouabain and potassium-free solutions on rat mesenteric resistance vessels., Circulation Research, 51:4, (514-524), Online publication date: 1-Oct-1982. NILSSON H and FOLKOW B (1982) Vasoconstrictor nerve influence on isolated mesenteric resistance vessels from normotensive and spontaneously hypertensive rats, Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1982.tb07131.x, 116:2, (205-208), Online publication date: 1-Oct-1982. Travo P, Weber K and Osborn M (1982) Co-existence of vimentin and desmin type intermediate filaments in a subpopulation of adult rat vascular smooth muscle cells growing in primary culture, Experimental Cell Research, 10.1016/0014-4827(82)90321-4, 139:1, (87-94), Online publication date: 1-May-1982. Mulvany M (2009) BLOOD PRESSURE REGULATION AND CHARACTERISTICS OF SMALL ARTERIES IN HYPERTENSION, Acta Medica Scandinavica, 10.1111/j.0954-6820.1982.tb09871.x, 212:S670, (21-28) Smith P, Wall Poston C and Mills E (1982) Abnormal functional development of sympathetic nerve terminal-smooth muscle complex in neonatal spontaneously hypertensive rats, Life Sciences, 10.1016/0024-3205(82)90545-8, 31:9, (889-892), Online publication date: 1-Aug-1982. MULVANY M, NILSSON H, NYBORG N and MIKKELSEN E (1982) Are isolated femoral resistance vessels or tail arteries good models for the hindquarter vasculature of spontaneously hypertensive rats?, Acta Physiologica Scandinavica, 10.1111/j.1748-1716.1982.tb07141.x, 116:3, (275-283), Online publication date: 1-Nov-1982. Evan A, Luft F, Gattone V, Connors B, MaCarron D and Willis L (1981) The glomerular filtration barrier in the spontaneously hypertensive rat., Hypertension, 3:3_pt_2, (I154), Online publication date: 1-May-1981.Bohr D (1981) What makes the pressure go up? A hypothesis., Hypertension, 3:6_pt_2, (II-160), Online publication date: 1-Nov-1981. Mulvany M, Korsgaard N and Nyborg N (2009) Evidence that the Increased Calcium Sensitivity of Resistance Vessels in Spontaneously Hypertensive Rats is an Intrinsic Defect of Their Vascular Smooth Muscle, Clinical and Experimental Hypertension, 10.3109/10641968109033699, 3:4, (749-761), Online publication date: 1-Jan-1981. MULVANY M and NYBORG N (2012) AN INCREASED CALCIUM SENSITIVITY OF MESENTERIC RESISTANCE VESSELS IN YOUNG AND ADULT SPONTANEOUSLY HYPERTENSIVE RATS, British Journal of Pharmacology, 10.1111/j.1476-5381.1980.tb10977.x, 71:2, (585-596), Online publication date: 1-Feb-1980. September 1980Vol 2, Issue 5 Advertisement Article InformationMetrics Copyright © 1980 by American Heart Associationhttps://doi.org/10.1161/01.HYP.2.5.664PMID: 7419268 Originally publishedSeptember 1, 1980 PDF download Advertisement