Abstract
The invariable occurrence of gingivitis in pregnancy initiated the present study of the local effects of sex hormones, deposited in the tissues. Vital microscopic studies of hamster's cheek pouch disclosed varying degrees of tissue injury manifested by mierocirculatory disturbances and related to the type and concentration of the hormones Gonadex®, Ovex‐B®, Stilbol® and Progesteron®. There were changes in blood flow, the behaviour of cells in the vessels and in the vessel walls and in the perivascular mast cells. Some of these abnormalities were reversible whereas others were permanent and severe.
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