Changes in Left Ventricular Function in Alcoholic Beverage Drinkers

Tomon Thongsri,Prawpan Suwanakitch,Chutiwan Jaichuen,Kanjana Jittiporn

doi:10.17485/ijst/2018/v11i12/121225

Abstract

Background: Chronic excessive alcohol consumption could lead to the progressive cardiac dysfunction known as Alcoholic cardiomyopathy (ACM). An evaluation form for the assessment of alcohol problems (Alcohol Use Disorders Identification Test: AUDIT) is a simple tool to screen alcohol problems for primary care. However, the link between the use of AUDIT and the diagnosis of heart disease in Thailand is limited. Objective: This study aimed to evaluate the left ventricular function of alcoholic beverage drinkers by echocardiography according to the severity of alcoholic consumption. Methods: Sixty regular alcoholic beverage drinkers, aged over 20 and living in Tambol Thapho, Muang, Phitsanulok Province, was enrolled in this study from January to May 2016. Data was collected from interviews regarding general information. The AUDIT evaluation form was used to assess alcohol problems, physical examinations, and echocardiography were performed. Echocardiographic measurement data were compared between the alcohol beverage drinkers group and a control group. Finding: The Left Ventricular Internal Diameter (LVID) of alcoholic beverage drinkers with AUDIT score levels of 2, 3 and 4 were significantly higher than the control group (at p<0.05, p<0.05, p<0.05, respectively).The Left Ventricular Ejection Fraction (LVEF) (Teicholz), of alcoholic beverage drinkers with an AUDIT score of level 4 was significantly lower than the control group (p<0.05). Moreover, the percentage of alcoholic beverage drinkers with abnormal left ventricular diastolic dysfunction with AUDIT score levels of 1, 2, 3 and 4 were 33.33%, 46.67%, 46.67% and 46.67%, respectively. Application: The present study demonstrated alcoholic beverage drinkers had systolic and diastolic dysfunctions. Therefore, the AUDIT evaluation form may be beneficial to screen for the risk of heart failure in alcoholic beverage drinkers in primary health care. Keywords: Alcohol Use Disorders Identification Test, Alcohol consumption, Alcoholic cardiomyopathy, Diastolic dysfunction, Systolic dysfunction

Highlights

Alcohol consumption caused about 2.7 million deaths and 3.9% of Disability-Adjusted Life Years (DALYs) in 2010
The Left Ventricular Internal Diameter (LVID) of alcoholic beverage drinkers with Alcohol Use Disorders Identification Test (AUDIT) score levels of 2-4 was significantly higher than the control group (p
There was no difference between AUDIT score levels in early diastolic filling velocity (E velocity), late diastolic filling velocity (A velocity), Deceleration Time (DT), Isovolumic Relaxation Time (IVRT), ratio of peak early diastolic velocity to late diastolic velocity of mitral inflow (E/A ratio), early diastolic velocity at Left ventricular (LV) basal septal segment (E’ septal), early diastolic velocity at LV basal lateral segment (E’ lateral), ratio of peak early diastolic velocity to early diastolic velocity at LV basal septal segment (Septal E/E’) and ratio of peak early diastolic velocity to early diastolic velocity at LV basal lateral segment (Lateral E/E’)

Summary

Introduction

Alcohol consumption caused about 2.7 million deaths and 3.9% of Disability-Adjusted Life Years (DALYs) in 2010. There are many diseases resulting from alcohol consumption occurring in the gastro-intestinal system The link between the results of an AUDIT evaluation and the diagnosis of heart disease by echocardiography in Thailand is not available due to a lack of data. This study aimed to evaluate the LV function of alcoholic beverage drinkers by echocardiography according to the AUDIT evaluation form. Objective: This study aimed to evaluate the left ventricular function of alcoholic beverage drinkers by echocardiography according to the severity of alcoholic consumption. The AUDIT evaluation form may be beneficial to screen for the risk of heart failure in alcoholic beverage drinkers in primary health care

Objectives

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Results

Conclusion