Abstract
The potassium, magnesium, and calcium contents of subcellular fractions of skeletal muscle from chronically morphinized rats and from control rats have been determined. In muscle from chronically morphinized rats abnormally high concentrations of potassium (3 × normal) and of magnesium (2× normal) are found in the microsomal fraction. Calcium concentration in this fraction is slightly raised. No such changes are observed in the composition of the nuclear and mitochondrial fractions.
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