Changes in hepatosomatic index and histoarchitecture of liver in common carp exposed to organophosphate insecticide sumithion

Md Idris Miah,Md Sadiqul Islam,Md Shahjahan,Sabrina Hossain

doi:10.3329/ajmbr.v2i2.29006

Md Idris Miah, Md Sadiqul Islam + Show 2 more

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https://doi.org/10.3329/ajmbr.v2i2.29006

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Abstract

Sumithion is widely used in larval rearing aquaculture ponds to control aquatic insects. This experiment was carried out to evaluate the effect of sumithion on hepatosomatic index and liver morphology in common carp, Cyprinus carpio. Acute toxicity of sumithion (96 h LC50 value) was first determined and it was 8.05 ppm for common carp. The fish were exposed to two sub-lethal concentrations (0.85 and 1.7ppm) of sumithion for a period of 21 days. A control set was also run for the same time with the same number of fish without sumithion (0 ppm). There was a marked increase in the hepatosomatic index in both concentrations (0.85 and 1.70 ppm) compared to control (0 ppm). Several histological changes of liver, such as necrosis, patchy degeneration, degenerated hepatocytes, vaculation and blood spilling were observed after exposure to sumithion with dose and exposure time dependent manner. The present investigation revealed the toxic potentiality of sumithion on common carp which alters liver morphology that may lead metabolic changes in fish.Asian J. Med. Biol. Res. June 2016, 2(2): 164-170

Highlights

In the last few decades, indiscriminate use of insecticides has raised the risk of contamination of environment as well as aquatic habitat
An effort was made to examine the effects of sumithion on the common carp (Cyprinus carpio), an economically important freshwater fish species contributing significant part in aquaculture for its high growth rate and palatability, by analysis of changes of hepatosomatic index (HSI) and liver histology
We demonstrated histological changes in liver of this fish species exposed to organophosphate pesticide Malathion (Sharmin et al, 2015)

Summary

Introduction

In the last few decades, indiscriminate use of insecticides has raised the risk of contamination of environment as well as aquatic habitat. Though they have been used for the safety of humans, their harmful effects on other non-target animals like fish are alarming. Sumithion, the O, O Dimethyl O-(3-methyl-4-nitrophenyl) is important one which falls under the organophosphate groups. In aquaculture, it is widely used in larval rearing pond to control harmful aquatic insect, tiger bug. An effort was made to examine the effects of sumithion on the common carp (Cyprinus carpio), an economically important freshwater fish species contributing significant part in aquaculture for its high growth rate and palatability, by analysis of changes of hepatosomatic index (HSI) and liver histology

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