Abstract
As part of a continuing study on changes in the neuromuscular system produced by the bite of the Rocky Mountain wood tick, it has been shown that the frequency of appearance of miniature end-plate potentials at paralyzed junctions was normal although their mean amplitude was larger, but the increase in their frequency which follows depolarization of the endings by potassium ions was much reduced. In magnesium-poisoned muscles the mean quantal content of end-plate potentials which could be evoked was normal. The changes observed could indicate a defect in the mobilization and/or release of acetylcholine at the terminals, but might conceivably be secondary to the previously demonstrated deficit of conduction in motor axons.
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