Abstract

Enzyme activities were studied over a period of time after feeding with a commercial pellet either once (I) or twice (II) a day. In both I & II, intestinal protease activity increased after the first feeding with a maximum at 5-7.5 hr. Amylase activity also reached a maximum at 5-7.5 hr, although it decreased temporarily after each feeding. Hepato-pancreatic protease decreased immediately and at 5-7.5 hr, recovering 10.5hr after the first feeding in both I & II. Hepatopancreatic amylase in I showed minimal activity after 5 hr with recovery thereafter. In II, at 5 hr after the second feeding, the level of activity was still far lower than the original one. It was concluded that the synthesis and secretion of enzymes in response to feeding is not transient, and that there is a time lag between the decrease in the amount of food in the digestive tract and the increase in the activity of the digestive enzymes.

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