Abstract
The kinetics of 3H-actinomycin D (AMD) binding to the nuclear deoxyribonucleoprotein (DNP) of male germ cells were studied by means of quantitative autoradiography. A progressive decrease in the ability of DNP to bind 3H-AMD occurred as the nucleus matured and condensed during spermiogenesis. The physical and chemical changes known to occur in the DNP complex at this time are thought to be responsible for this reduction in binding rate.
Published Version
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