Abstract
Magnesium, orthophosphate and fluoride salts were added singly or in combinations to high-sucrose cariogenic diets in rats. Both the orthophosphate and fluoride, when added singly, reduced the incidence of caries. However, the greatest caries reductions (maximum 94 per cent) were obtained by combinations of all three additives. Dental calculus formation was increased by phosphate and slightly reduced by fluoride singly. The enhancement of calculus formation, caused by phosphate, tended to be reduced by further addition of the other factors, magnesium and fluoride.
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