Abstract
Cytophotometry of RNA was carried out in neurons of the cranial cervical sympathetic ganglion of mature rabbits treated with different doses of the ganglion-blocker Dimecoline. After injection of the drug sharp fluctuations in the RNA content were observed in the cytoplasm of the neurons. The course of the fluctuations differed significantly depending on the dose of the drug injected, but it was similar in mono- and binuclear neurons. It is concluded from analysis of the character of differences found in the investigation that the results support the hypothesis of the leading role of synaptic processes in the formation of quantitative changes in the RNA content in the postsynaptic neuron. The results are evidence of increased functional activity of some ganglionic neurons after administration of different doses of Dimecoline both during and after the end of the block.
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