Abstract
The use of marihuana is becoming more frequent in young people, the association between psychosis and cannabis has been described, especially in young people, we present a clinical case of psychosis associated with cannabis in a young man with normal Brain Magnetic resonance, but abnormalities in tractography mainly in the connectivity between cuadate nucleus and frontal lobe.
Highlights
Several longitudinal population studies strongly association between cannabis and psychosis, in individuals who begin consumption before adulthood [1].The Cannabis is the most common used drug among young people, the rates recorded around of the onset of psychosis as between 35-45%, the continued use of marihuana following onset of psychosis is associated with poorer outcomes, delays in remission, suicidal behaviour, violence [2].In prospective investigations in first-episode psychosis cannabis users an Australian study report a 51% relapsed rate over 15 months follow-up among users compared with 17% among non-users [3]
Despite the reporting of earlier age at psychosis onset in cannabis users, the exact reason for this clinical condition has not yet been established, but an increase in cannabinoids CB1 receptors density in prefrontal áre as during adolescence has been proposed to be responsible in vulnerable patients [6]
We present a clinical case with psychosis in cannabis user and abnormlities in tractography
Summary
Several longitudinal population studies strongly association between cannabis and psychosis, in individuals who begin consumption before adulthood [1].The Cannabis is the most common used drug among young people, the rates recorded around of the onset of psychosis as between 35-45%, the continued use of marihuana following onset of psychosis is associated with poorer outcomes, delays in remission, suicidal behaviour, violence [2].In prospective investigations in first-episode psychosis cannabis users an Australian study report a 51% relapsed rate over 15 months follow-up among users compared with 17% among non-users [3]. In prospective investigations in first-episode psychosis cannabis users an Australian study report a 51% relapsed rate over 15 months follow-up among users compared with 17% among non-users [3].
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