Abstract
The present study was carried out to clarify whether caffeine affects cerebral hemodynamics in the prefrontal cortex association area in young male subjects during a cognitive task. Relative changes in blood volume and oxygenation in the prefrontal association cortex were measured noninvasively using continuous-wave near-infrared spectroscopy. A modified Stroop color-word task we developed was employed as a cognitive task to activate the prefrontal association cortex. The results showed that caffeine ingestion affects cerebral hemodynamics during the modified Stroop task, and suggested that the decrease in oxygenated hemoglobin may be related to deterioration of performance on the cognitive task following caffeine ingestion.
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