Abstract
These results demonstrate the magnitude of the adrenergic stimulation during shock in man. Such stimulation leads to a rise in plasma catecholamines and to a relative impoverishment of the catecholamine stores in the adrenal medulla. The clinical effectiveness of this stimulation is, however, not evident in every case. From a clinical point of view, the state of shock and the subsequent hypercatecholaminaemia are not necessarily related to a severe decrease in the arterial blood pressure. On the other hand, a reduction in the urine output goes with the highest plasma catecholamine levels.
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