Abstract
We aimed to study the effects of inspiratory muscle training (IMT) as add-on to pulmonary rehabilitation (PR) on breathing pattern during maximal cardiopulmonary exercise testing (CPET). Methods: 25 COPD patients (FEV1=51±17%pred; PImax=65±12%pred) performed 8 weeks of IMT program during PR. 25 matched control subjects (age, gender, FEV1, PImax and exercise capacity) who had participated in an identical PR program without IMT were selected retrospectively. Results: Patients performing IMT during PR had significantly larger increases in PImax, peak work rate and peak ventilation with comparable dyspnea scores at peak exercise after PR (see table). Differences in breathing frequency (BF) and tidal volume (VT) pre-post intervention in IMT (1A+1B) and control group (2A+2B) are illustrated below. Significant differences in BF (p=0.017) and VT (p=0.002) at iso-ventilation (80% peak ventilation pre-test) were observed between IMT and control group. Conclusion: The addition of IMT to a PR program in COPD patients with inspiratory muscle weakness resulted in favorable changes in breathing pattern during whole body cycle exercise.
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