Abstract
Patients in intensive care units (ICUs) are treated with intravenous (IV) insulin by infusions with the goal of maintaining blood glucose (BG) within a narrow target range. However, as BG is measured intermittently and how the time course of BG concentration changes after altering the insulin infusion rate is unknown. We used an intra-arterial Continuous Glucose Monitoring (CGM) system to study the time course of BG concentrations after changes in IV insulin infusion rates.
Highlights
Patients in intensive care units (ICUs) are treated with intravenous (IV) insulin by infusions with the goal of maintaining blood glucose (BG) within a narrow target range
We analysed BG values measured by the Continuous Glucose Monitoring (CGM) system following a step-wise change in the insulin infusion rate for a maximum of 2 hours
There were 5 episodes where the insulin infusion was decreased by 1 u/hr, BG remained relatively stable until 90 mins after which time there was a marked variability
Summary
Changes in blood glucose concentrations over time when administering intravenous insulin in post cardiac surgery in adult intensive care patients Introduction Patients in intensive care units (ICUs) are treated with intravenous (IV) insulin by infusions with the goal of maintaining blood glucose (BG) within a narrow target range. As BG is measured intermittently and how the time course of BG concentration changes after altering the insulin infusion rate is unknown. We used an intra-arterial Continuous Glucose Monitoring (CGM) system to study the time course of BG concentrations after changes in IV insulin infusion rates.
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