CHANGES IN BIOCHEMICAL COMPOSITION OF BLOOD IN THE TREATMENT OF POSTPARTUM ENDOMETRITIS IN COWS

Abstract

Postpartum complications are recorded in 40–80 % of cases of calving animals. A prerequisite for this is a metabolic disorder that affects the morpho biochemical status of the body. The use of drugs based on probiotic microorganisms for the treatment and prevention of obstetric and gynecological pathology is a promising direction. Therefore, the aim of our research was to study the changes in hematological parameters in the treatment of acute postpartum endometritis in cows with the use of a new probiotic drug. We developed drug Fometrin suppositories is a light yellow color, with a content of dry biomass of probiotic cultures of cells. Fometrin the drug were injected 3 or 4 candles of the first and second experimental groups of cows, respectively, 1 per day, intrauterine, for 5–7 days, also used the PDE to 20 ml and Uteroton 10 ml, 3 times in 48 hours. For treatment of control animals used Ichglukovit, Oksilat and PDE in accordance with the instructions for use. As a result, the largest number of recovered animals (80 %) was in the second experimental group, the independence period was 28 % and the service period was 31 % and the index of insemination by 15 % than in control. The use of endometritis therapy regimen with the drug Fometrin in comparison with traditional treatment, manifested a decrease in the content of leukocytes by an average of 26.9 % and an increase in the number of segmental neutrophils by an average of 36 %, as well as a more optimal level of nonspecific resistance of the body, determined by the ratio of lymphocytes to rod neutrophils, to the end of the experiment. After treatment there was an increase in iron content on average by 20.5 % and cholesterol by 27.6 % in the experimental groups of cows and the most pronounced changes in the indices of protein and mineral metabolism in the organism of animals second experimental group.