Abstract
1. 1. Alkaline deoxyribonuclease activity has been determined at different stages of embryonic development of the sea urchin Paracentrotus lividus. The enzyme level remains almost constant until the hatching blastula stage; a sudden decrease occurs between late blastula and the onset of gastrulation. From the gastrula stage on, a progressive increase in the activity is observed. 2. 2. The enzymatic activity pattern parallels DNA synthesis: the decrease in DNAse activity corresponds to a decline in mitotic activity during gastrulation. 3. 3. The suggestion is made that DNAse might act as a factor controlling DNA synthesis. Possible role of the enzyme in the differentiation of the digestive system is also discussed.
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