Changes associated with the organization of motor acts in the on-going frequency of the discharges of neurons of subcortical structures of the human brain.

Abstract

The impulse activity of subcortical structures was recorded in 16 parkinsonian patients (six women) using deep electrodes implanted in the strio-pallido-thalamic system on the basis of treatment and diagnostic indications. The patients voluntarily participated in four psychological tests. Two groups of pallidal and thalamic neuronal populations (neuronal populations associated with the response and associated with the stimulus, containing 25% each out of the total number of neuronal populations recorded) were classified on the basis of evoked changes in on-going frequency in the motoric version of the odd ball test. Some of the neuronal populations associated with the response reacted primarily during counting, some during the naming of the stimulus, and some during button pressing.