Change of surgical procedure for thyroid tumor after collaboration with Nagasaki (Japan) and Semipalatinsk (Kazakhstan).

Abstract

e17590 Background: From 1949 to 1989, 456 nuclear tests were conducted by the former Soviet Union at the Semipalatinsk Nuclear Test Site (SNTS) in Kazakhstan. It is very important to assess the clinical behavior of thyroid cancer which may be affected by SNTS in the control of an accurate diagnosis and standardized surgery. We have collaborated with the Semipalatinsk Oncology Center since 1999, in order to establish an optimal method to diagnose and perform a thyroidectomy and a lymph node dissection for the patients with papillary thyroid cancer that is better suited for the Semipalatinsk environmental effects. Methods: To assess the change of diagnostic accuracy and thyroid surgery from 1999 to 2010 in Semipalatinsk Oncology Center in collaboration with Nagasaki University and Nagasaki Medical Center. Material: A total of 200 patients with thyroid cancer who underwent thyroid surgery at the Semipalatinsk Oncology Center were evaluated. From the 200 patients, 145 patients with papillary thyroid cancer were assessed for surgical procedure. This was a cross-sectional observational study. Results: 1) Before 2001, there were few preoperatively diagnosed thyroid cancers and from 2002, preoperatively diagnosed papillary cancers increased. 2) The partial lobectomies were mainly performed until 2001. From 2002 to 2010, total lobectomies were chosen for the majority of the patients, but total thyroidectomies were rarely performed. 3) Up to 2014, there are no local and distant metastasis were seen in those patients with papillaty cancer. Conclusions: An accurate diagnosis and standardized surgery for thyroid cancer helped to evaluate the biological characteristics of thyroid cancer which may be affected by SNTS in next decade.