Abstract
The effects of paraquat (PQ)on the contents of putrescine (PUT), spermidine (SPD) and spermine (SPM) in the various tissues and organs were examined by means of high-performance liquid chromatography in rats intoxicated with the toxin by three intraperitoneal infusions of PQ for 6 days on every other day. The contents of PUT, SPD and SPM in the large intestine per mg of wet weight showed statistically significant decreases of 39 ( P < 0.01), 73 ( P < 0.01) and 27% ( P < 0.05), respectively. In the liver, however, they showed statistically significant increases of 214 ( P < 0.01), 39 ( P < 0.05) and 78% ( P < 0.01).
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