Abstract
Purpose Recent studies have implicated low vitamin D levels with greater disease activity in pediatric systemic lupus erythematosus (SLE) and we have reported an association between low vitamin D levels and greater disease activity in juvenile dermatomyositis. The objective of this study was to explore whether standardized vitamin D supplementation of low levels of 25-hydroxyvitamin D [25(OH)D] might be associated with improvements in disease activity.
Highlights
ObjectivesThe objective of this study was to explore whether standardized vitamin D supplementation of low levels of 25-hydroxyvitamin D [25(OH)D] might be associated with improvements in disease activity
Recent studies have implicated low vitamin D levels with greater disease activity in pediatric systemic lupus erythematosus (SLE) and we have reported an association between low vitamin D levels and greater disease activity in juvenile dermatomyositis
All subjects with serum 25(OH)D levels less than 30ng/mL were given ergocalciferol 50,000 IU weekly for 8 weeks, and serum 25(OH)D levels, physician’s global assessment (PGA), and SLE disease activity index (SLEDAI) were reevaluated at their routine follow up visit
Summary
The objective of this study was to explore whether standardized vitamin D supplementation of low levels of 25-hydroxyvitamin D [25(OH)D] might be associated with improvements in disease activity
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