Abstract
Approximately 5% of COVID-19 patients will have a severe disease requiring invasive or non-invasive mechanical ventilation. In this conditions, sedatives and analgesics are fundamental to promote tolerance, comfort and synchrony with the mechanical ventilator. High and unusual requirements for sedation, analgesics and neuromuscular blockers have been reported in these patients, contributing to prolonged exposure, a high rate of delirium and prolongation of mechanical ventilation. These factors, added to the progressive shortage of these drugs, a high demand for care and less capacity for personalized attention, have created an adverse scenario for their proper and rational use. This paper proposes different pharmacotherapeutic optimization strategies for a rational management of sedation, analgesia and neuromuscular block in critically ill patients with COVID-19, with the therapeutic alternatives available in Chile.
Highlights
La enfermedad por coronavirus 2019 (COVID-19) es una condición globalmente emergente causada por el agente infeccioso SARS-CoV-21, el que debido a su rápida expansión ha afectado a más de 8,5 millones de personas en el mundo, de las cuales aproximadamente medio millón han fallecido[2]
This paper proposes different pharmacotherapeutic optimization strategies for a rational management of sedation, analgesia and neuromuscular block in critically ill patients with COVID-19, with the therapeutic alternatives available in Chile
Devlin J, O’Neal H, Thomas C, Barnes D, Mary A, Stollings J, et al Strategies to Optimize ICU Liberation (A to F) Bundle Performance in Critically Ill Adults With Coronavirus Disease 2019, Crit Care Expl
Summary
Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile. 5% of COVID-19 patients will have a severe disease requiring invasive or non-invasive mechanical ventilation. High and unusual requirements for sedation, analgesics and neuromuscular blockers have been reported in these patients, contributing to prolonged exposure, a high rate of delirium and prolongation of mechanical ventilation. These factors, added to the progressive shortage of these drugs, a high demand for care and less capacity for personalized attention, have created an adverse scenario for their proper and rational use. This paper proposes different pharmacotherapeutic optimization strategies for a rational management of sedation, analgesia and neuromuscular block in critically ill patients with COVID-19, with the therapeutic alternatives available in Chile. La Región Metropolitana, la más afectada en el desarrollo de esta pandemia, reporta 1.276 pacientes en Unidades de Cuidado Intensivo (UCI), acumulando 73,71% del total nacional, con un porcentaje de ocupación de camas críticas mayor a 90%3
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
