Abstract

AbstractThe design of single‐use and single‐use/stainless‐steel hybrid systems require attention to the routing of hoses and cables. Commercial solutions are available, but customized, technically simple solutions are often successful. For hybrid systems, status “functionally closed” is often required. Chemical sanitization compared to steam sanitization includes improved process reliability and handling. In this contribution, examples of design solutions and recommendations for efficient and safe design and operation of single‐use/stainless‐steel hybrid plants are provided.

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