Abstract
Challenges in Skeletal Muscle Physiology
Highlights
Major gaps exist in our understanding of fundamental mechanisms underlying contraction, as well as of mechanisms that contribute to the control of muscle physiological properties
Evidence has accrued to support a role for an interaction between myosin binding protein-C (MyBP-C) and myosin in modulating skeletal and cardiac muscle contraction (e.g., Hofmann et al, 1991a,b; Luther et al, 2008)
It has been reported that interactions of MyBP-C with actin could have a modulatory role in contraction in cardiac muscle (Shaffer et al, 2009; Shchepkin et al, 2010) and this raises the possibility of a related mechanism in skeletal muscle
Summary
Major gaps exist in our understanding of fundamental mechanisms underlying contraction, as well as of mechanisms that contribute to the control of muscle physiological properties. Evidence has accrued to support a role for an interaction between MyBP-C and myosin in modulating skeletal and cardiac muscle contraction (e.g., Hofmann et al, 1991a,b; Luther et al, 2008).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
