Challenges, Biases, and Limitations in Systematic Reviews and Meta-Analyses: Addressing Pitfalls in Medical Research Methodologies

Abstract

Abstract: Systematic reviews and meta-analyses represent crucial tools in medical research, synthesizing vast arrays of data to inform clinical and policy decisions. While their merits are undeniable, potential pitfalls, biases, and limitations threaten the integrity of these methodologies. This paper explores common challenges faced in the execution and interpretation of systematic reviews and meta-analyses, emphasizing strategies to enhance the robustness and reliability of future research.