Abstract

Functional neurosurgery techniques remain integral to the neurosurgical treatment armamentarium but data on global implementation remains scarce. In comparison to high-income countries (HIC), low- and middle-income countries (LMIC) suffer from an increased prevalence of diseases like epilepsy, which may be amenable to functional techniques, and therefore, LMIC may benefit from an increased utilization of these treatment modalities. However, functional techniques tend to be expensive and thus difficult to implement in the LMIC setting. A review was performed to assess the current status of functional neurosurgical techniques in LMIC as a starting point for future initiatives.For methodology, a review of the current body of literature on functional neurosurgery in LMIC was conducted through the United States National Library of Medicine Pubmed search engine. Search terms included “functional neurosurgery,” “developing countries,” “low and middle income,” and other related terms.It was found that though five billion people lack access to safe surgical care, the burden of disease amenable to treatment with functional neurosurgical procedures remains unknown. Increasingly, reports of successful, long-term, international neurosurgical collaborations are being reported, but reports in the sub-field of functional neurosurgery are lacking.In conclusion, awareness of global surgical disparities has increased dramatically while global guidelines for functional techniques are currently lacking. A concerted effort can harness these techniques for wider practice. Partnerships between centers in LMIC and HIC are making progress to better understand the burden of disease in LMIC and to create context-specific solutions for practice in the LMIC setting, but more collaborations are warranted.

Highlights

  • BackgroundFor most of the 20th century and increasingly so in the 21st century, functional procedures have remained integral to the neurosurgical armamentarium, allowing the treatment of many pathologies, including epilepsy, Parkinson’s disease, other movement disorders, painHow to cite this article Fezeu F, Ramesh A, Melmer P D., et al (September 17, 2018) Challenges and Solutions for Functional Neurosurgery in Developing Countries

  • In comparison to highincome countries (HIC), low- and middle-income countries (LMIC) suffer from an increased prevalence of diseases like epilepsy, which may be amenable to functional techniques, and LMIC may benefit from an increased utilization of these treatment modalities

  • The burden of disease is higher in LMIC for conditions amenable to functional procedures, for example, the prevalence of epilepsy is higher in LMIC than in high-income countries (HIC) [6]

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Summary

Introduction

For most of the 20th century and increasingly so in the 21st century, functional procedures have remained integral to the neurosurgical armamentarium, allowing the treatment of many pathologies, including epilepsy, Parkinson’s disease, other movement disorders, pain. The centers within the United States conducted a greater number of vagal stimulation surgeries than those in Europe or Australia, and they operated more often going off of fewer magnetic resonance imaging (MRI) findings in the patients but utilized intracranial electrodes and neuroimaging more frequently than the other two regions [18] These data present a compelling glance at the diverse protocols in HIC and could be useful in the development of worldwide standards to be utilized by LMIC doing pediatric functional neurosurgery. This experience demonstrates that standardized protocols can be successfully implemented in LMIC and that functional neurosurgery is feasible with the equipment already available in some countries. Innovation from LMIC has resulted in an improvement in other fields of neurosurgery and there is no reason to suspect functional neurosurgery will be any different

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