Abstract
Allylrhodium species derived from δ‐trifluoroboryl β,γ‐unsaturated esters undergo chain walking towards the ester moiety. The resulting allylrhodium species react with imines to give products containing two new stereocenters and a Z‐alkene. By using a chiral diene ligand, products can be obtained with high enantioselectivities, where a pronounced matched/mismatched effect with the chirality of the allyltrifluoroborate is evident.
Highlights
Allylrhodium species derived from d-trifluoroboryl b,g-unsaturated esters undergo chain walking towards the ester moiety
The migration of metal centers along carbon chains occurs in several important reactions.[1,2,3,4,5,6,7]
Many of these migrations take place by b-hydride elimination and hydrometalation sequences, in which the direction of travel is controlled by thermodynamics, a ligand, or a nearby functional group
Summary
Allylrhodium species derived from d-trifluoroboryl b,g-unsaturated esters undergo chain walking towards the ester moiety. [d] In the unpurified reaction, traces of a product derived from allylation without chain walking were detected.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
