Chain photosolvation of trans,trans,trans-[PtIV(py)2(N3)2(OH)2] complex prospective as a light-activated antitumor agent

Grigory I Zhdankin,Vjacheslav P Grivin,Victor F Plyusnin,Pavel A Tkachenko,Danila B Vasilchenko,Evgeni M Glebov

doi:10.1016/j.mencom.2023.01.019

Chain photosolvation of trans,trans,trans-[PtIV(py)2(N3)2(OH)2] complex prospective as a light-activated antitumor agent

Grigory I Zhdankin, Vjacheslav P Grivin + Show 4 more

Open Access

https://doi.org/10.1016/j.mencom.2023.01.019

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Journal: Mendeleev Communications	Publication Date: Jan 1, 2023
Citations: 7

Affiliation: Institute of Chemical Kinetics and Combustion, Novosibirsk State University, Nikolaev Institute of Inorganic Chemistry

#Laser Flash Photolysis #Multistage Process + Show 7 more

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Abstract

The photochemistry of a potential light-activated anticancer complex, trans,trans,trans-[PtIV(py)2(N3)2(OH)2], was explored by steady-state and laser flash photolysis. The photolysis was a multistage process with the formation of complexes trans-[PtIV(py)2(N3)(OH)2(H2O)]+ and/or trans-[PtIV(py)2(N3)(OH)3] due to chain photoaquation at the first stage.

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