Abstract
Multilamellar dispersions from a new synthetic phospholipid, 1,2-dimyristoyl-sn-glycero-3-phosphoglucose (DMPGE), bearing a glucose ring in the polar headgroup, are studied by means of FTIR, 2H, and 31P NMR spectroscopy. The investigations are focused on the evaluation of the molecular ordering of the lipid molecules as a function of temperature and cholesterol content. Information about the conformational order of the acyl chains is obtained from variable temperature FTIR investigations. Analysis of the CH2 stretching and wagging modes of nondeuterated compounds provides the relative changes in conformational order in the vicinity of the main transition and integral values of distinct gauche conformers over the whole acyl chains, respectively. Likewise, CD2 rocking bands are used to derive the amount of gauche conformers at a specific chain segment in samples containing selectively deuterated acyl chains. The present work represents the first report where the orientational order parameter simultaneously ...
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