Abstract
ABSTRACTBackground We investigated the mortality rates of patients with Chagas disease (CD) during the coronavirus disease 2019 (COVID-19) pandemic and assessed the association between this mortality and CD clinical presentation and comorbidities. Methods: This was an observational retrospective study with clinical data retrieved from medical records. Results: Comorbidities were more prevalent among patients who died from COVID-19 than those who died from other causes. The proportion of patients according to CD clinical presentation was similar between the two groups. Conclusions: The prevalence of comorbidities seems to be related to a poorer prognosis in CD and COVID-19.
Highlights
We investigated the mortality rates of patients with Chagas disease (CD) during the coronavirus disease 2019 (COVID-19) pandemic and assessed the association between this mortality and CD clinical presentation and comorbidities
This study aimed to describe the mortality rates of patients with CD at an infectious disease referral center in Brazil during the COVID-19 pandemic, and investigate its association with CD clinical presentation and comorbidities
According to the clinical presentation of CD, there was no significant difference in the proportion of patients who died from COVID-19 and those who died from other causes (Table 1)
Summary
We investigated the mortality rates of patients with Chagas disease (CD) during the coronavirus disease 2019 (COVID-19) pandemic and assessed the association between this mortality and CD clinical presentation and comorbidities. Hasslocher-Moreno AM et al - Chagas disease mortality and COVID-19 and SARS-CoV-2 coinfection can increase the pathogenic process, worsening CHD.
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