Abstract
In this session, new insights in the structure, the function and the regulation of cystic fibrosis transmembrane conductance regulator (CFTR) were discussed. A special emphasis was to examine in more detail the recent findings on the interaction between CFTR and the epithelial sodium channel (ENaC). How does ENaC interact with CFTR? Is this interaction direct or indirect? What is the physiological and pathophysiological relevance of the ENaC/CFTR interaction in different epithelial tissues?
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