Abstract
Sri Lanka Journal of Medicine is the official journal of the Kandy Society of Medicine. It is a peer-reviewed journal currently published biannually. Original articles, reviews, brief reports, case reports, points of view, and letters to the editor, in all fields of medical science and practice are accepted for publication.The Sri Lanka Journal of Medicine is now indexed in DOAJ
Highlights
Fixed drug eruption (FDE) was first described in 1889 and is described as a sudden eruption of annular, oedematous, dusky red macules or plaques on the skin and mucous membranes along with a burning sensation and itching that leave residual hyperpigmentation most commonly as a reaction to systemically administered drugs[1]
We report a patient with cetirizine induced FDE
A 15-year-old, previously healthy girl developed a burning and pruritic rash over the right forearm and right thigh one day after taking cetirizine tablets which she had been prescribed for a common cold
Summary
Fixed drug eruption (FDE) was first described in 1889 and is described as a sudden eruption of annular, oedematous, dusky red macules or plaques on the skin and mucous membranes along with a burning sensation and itching that leave residual hyperpigmentation most commonly as a reaction to systemically administered drugs[1]. The lesions recur on the same place with the re-introduction of the same drug. The lesions may be solitary or multiple. They may be bullous, pigmented, or non-pigmented[1]. The commonly implicated agents include antibacterial drugs, nonsteroidal anti-inflammatory drugs (NSAID), barbiturates and phenolphthalein. Cetirizine is commonly used piperazinederived, second-generation, non-sedative antihistamine[2]. Cetirizine-induced FDE is uncommon and has not been previously reported in Sri Lanka. We report a patient with cetirizine induced FDE
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