Cervical sarcoma botryoides and ovarian Sertoli–Leydig cell tumor: a case report and review of literature

Abstract

The diagnosis of two or more conditions in the same patient and in particular of the same system is always noteworthy because it raises the possibility to see a common etiopathogensis. A not very well known example is the association between cervical sarcoma botryoides and ovarian Sertoli–Leydig cell tumor. Daya and Scully [1] reported two cases of cervical rhabdomyosarcoma on 207 patients with ovarian Sertoly-Leydig cell tumors. Goldbang et al. [2] referred a case report of a 14-year-old patient, who had a sarcoma botryoides and who 13 years later developed an early ovarian Sertoli–Leydig. McClean et al. reported an other case of a 13-year-old patient with a cervical rhabdomyosarcoma concomitant of ovarian Sertoli–Leydig cell tumor; but none of these authors refer to a clear answer about a common pathogenesis [3]. In this report, we describe the case of a patient with a cervical relapse of sarcoma botryoides originally diagnosed in our hospital when she was 20 years old and 1 year before she had developed an ovarian Sertoli–Leydig cell tumors. A systematic review contained in a table of the published literature about this association is also showed. Although this is the fifth published case, the basis for this association is not clear. Case report