Abstract
Background: Cervical cancer is a leading cause of mortality and morbidity among women worldwide and most common gynaecological cancer in developing countries. Papanicolaou smear is a simple and cost effective screening test for cervical cancer. The aim of this study is to evaluate and interpret the cervical pap smear cytology in a tertiary hospital. The interpretation and reporting of the pap smear is based on 2001Bethesda system.Materials and methods: This is a prospective study conducted in a tertiary hospital, Nepal Medical College over a period of two and a half years (January 2013 to June 2015). All cervical pap smears received in the department of Pathology in the study period were included.Results: A total of 4160 cervical pap smears were reported in the study period. Majority of the cases were Negative for Intraepithelial lesion or malignancy (87.9%). Bacterial vaginosis, atrophy and reactive cellular changes associated with inflammation were seen in 5.3%, 2.4% and 1.5% cases respectively. Epithelial cell abnormalities (0.5%) include Atypical squamous cells of undetermined significance, Low grade squamous intraepithelial lesion and High grade intraepithelial lesion. 88% of Low grade squamous intraepithelial lesion was seen in reproductive age group (20-45 years).Conclusion: Cervical cancer is the most common gynaecological cancer in the developing countries. Pap smear is the simple and cost effective screening tool to detect pre invasive cervical epithelial lesions.
Highlights
Cervical cancer is the most common gynaecological cancer leading to death in developing countries like Nepal.[1,2] The World Health Organization (WHO) Information Centre on HPV (Human Papilloma Virus) and Cervical Cancer states the incidence of cervical cancer in Nepal is 24.2 per 100,000 making Nepal a country with one of the highest rates of Correspondence: In developing countries, the higher prevalence of cervical cancer is due to ineffective screening programmes
The World Health Organization (WHO) Information Centre on HPV (Human Papilloma Virus) and Cervical Cancer states the incidence of cervical cancer in Nepal is 24.2 per 100,000 making Nepal a country with one of the highest rates of Correspondence: Dr Sujata Pudasaini, MBBS, MD Assistant Professor, Department of Pathology Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal E-mail: sujatapudasaini@gmail.com cervical cancer in the world
The incidence of cervical cancer has decreased more than 50% in the past thirty years because of widespread screening with cervical cytology.[5]
Summary
Cervical cancer is the most common gynaecological cancer leading to death in developing countries like Nepal.[1,2] The World Health Organization (WHO) Information Centre on HPV (Human Papilloma Virus) and Cervical Cancer states the incidence of cervical cancer in Nepal is 24.2 per 100,000 making Nepal a country with one of the highest rates of Correspondence: In developing countries, the higher prevalence of cervical cancer is due to ineffective screening programmes. Pap smear is a simple, convenient, cost effective and reliable test for easy screening of cervical lesions. Since its introduction there has been a dramatic reduction in the incidence and mortality of invasive cervical cancer worldwide.[4,5,6]. This study is done to evaluate the pattern of cervical pap smear cytology and find out the incidence of epithelial cell abnormalities. Cervical cancer is a leading cause of mortality and morbidity among women worldwide and most common gynaecological cancer in developing countries. Papanicolaou smear is a simple and cost effective screening test for cervical cancer. The aim of this study is to evaluate and interpret the cervical pap smear cytology in a tertiary hospital. The interpretation and reporting of the pap smear is based on 2001 Bethesda system
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
