Abstract

(Abstracted from JAMA 2023;330(6):547–558) More than 90% of cervical cancer is caused by persistent infections with carcinogenic human papillomavirus (HPV), leading to precancer and then to cervical cancer. Approximately 100,000 people are treated for cervical precancer, 14,000 people are diagnosed with cervical cancer, and more than 4000 die of cervical cancer in the United States each year.

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