Abstract
It is clear that cervical cancer is caused by human papillomavirus (HPV) can largely be prevented by screening and could theoretically be eradicated through vaccination against HPV. The key public-health questions are how to implement effective screening in developing countries and how to fund and roll-out vaccination so that women born in the 21st century need not be plagued by this terrible disease. What factors affect the development of cervical cancer in women exposed to HPV? In 2005 a Working Group for the International Agency for Research on Cancer classified combined oral contraceptives as carcinogenic to the human uterine cervix (details are yet to be published). David Skegg wrote: From a public-health viewpoint a key question is the extent to which effects persist after women stop taking oral contraceptives. Skeggs challenge was to bring together all relevant data and quantify the duration of this effect and this is taken up in a study published in todays Lancet. (excerpt)
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