Cervical cancer in pregnancy: one case report and a review of current treatment recommendations

Abstract

A 37-year-old pregnant woman with poorly differentiated squamous cell carcinoma of the cervix is presented in this article. Abnormal vaginal bleeding was detected during the regular prenatal examination in the 15th gestational week, and a 2-cm cauliflower-like neoplasm was found in the cervix. Cervical biopsy suggested poorly differentiated squamous cell carcinoma of the cervix and HPV (human papillomavirus) type 16 was positive in the 21st gestational week. After three cycles of neoadjuvant chemotherapy with TP (paclitaxel + cisplatin) regimen, the pregnant woman had received a cesarean section in the 34 th gestational week, during which radical hysterectomy and pelvic lymphadenectomy was also performed. Metastasis was identified in the resected pelvic lymph nodes, and an additional 35 sessions of radiotherapy were applied after the surgery. No recurrence of cervical cancer has been found in the patient’s 24 months of follow-up visits.