Abstract

Relying on his own observations, the author discusses certain experimental and clinical problems of pyelonephritis. He demonstrates that infection in cases of ascending pyelonephritis is dissemeinated outside the lymph paths and not transmitted from one to another point of the kidney by the renal lymphatic apparatus. Accordingly, the term “interstitial progress” is suggested instead of “lymphogenic infection”. Animal expeeriments show that infection of varios organs induces acute pyelonephritis of focal necrosis in the kidney. It is suggested that renal lesions may be produced in a similar manner in human subjects and that their non-recognition may lead to latent chronic kidney diseases. The first part of the clinical chapter discusses prophylactic possibilities, in the first place the use of asymptomatic bacteriuria. The second part deals with a dietetic treatment of chronic nephropathies. A specific diet and the results of its employment are described.

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