Abstract
The consequences of destruction of the caudate nucleus were studied in rabbits and in dogs. Injections of molten paraffin into the above subcortical formation were used for that purpose (the puncture was performed through the brain cortex). It was considered that this may bring about disturbances similar to those which appear in brain tumors. It was demonstrated by the results of these experiments that the delicate function of motor coordination was disturbed in local destruction of the larger portion of the caudate nucleus. Sensitivity, both cutaneous and proprioceptive was, likewise, disturbed. Characteristic changes appeared in the animals' behavior. Conditioned reflexes were disturbed in rabbits, as well as in dogs.
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