Abstract
Cerium oxide nanoparticles (nanoceria) are reported to exhibit nanozyme activities, such as biological catalase, oxidase, superoxide dismutase, and peroxidase-mimetic activities. Nanoceria nanozymes own several advantages over natural enzymes, such as controlled synthesis at low cost, tunable catalytic activities, as well as high stability against strict physiological conditions. Exploiting these properties, several biomedical applications, such as bio-sensing, immunoassay, drug delivery, radiation protection, and tissue engineering, have been exercised. This chapter provides a comprehensive summary of reported biological enzyme-mimetic activities of nanoceria, the possible mechanisms of catalysis, as well as their biomedical applications.
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