Abstract

Spinal Cord Injury (SCI) results in significant cardiovascular autonomic dysfunction dependent on the level and completeness of lesion. Impaired cardiovascular control in SCI is associated with loss of sympathetic neural control of the heart and vasculature and can result in precipitous variations in blood pressure, such as Orthostatic Hypotension and Autonomic Dysreflexia. Individuals with SCI are at higher risk of cerebrovascular disease, such as stroke and transient ischemic attacks. Cerebral blood flow (CBF) is thought to remain relatively constant within a range of blood pressures, known as cerebral autoregulation (CA) which comprises two components; static and dynamic CA.

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