Abstract
AbstractOxidative stress has a significant impact on neurodegenerative diseases. The present paper reviewed the role of oxidative stress in disease progression of Alzheimer's disease (AD) and measurement of the oxidative stress markers in cerebrospinal fluid (CSF) in AD in vivo. Oxidative stress measurement in CSF in AD provides knowledge of underlying pathophysiology, to be a counterpart of oxidative stress neuroimaging, and to help differentiating AD from other neurodegenerative diseases. In addition, these findings warrant future studies to see whether antioxidant intervention might help preventing progression of neurodegenerative diseases including AD.
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