Abstract
ABSTRACT Objective: We report a case of cerebral venous thrombosis (CVT) associated with Graves hyperthyroidism in order to increase awareness of this association in the literature. CVT entails significant morbidity and mortality, and awareness of its risk factors may assist both with expediting its diagnosis and completing an appropriate workup. Methods: A 62-year-old female with a 3-week history of symptoms of hyperthyroidism secondary to Graves disease, and a 2-week history of treatment with methimazole, presented with sudden onset of severe headache, right-sided weakness, and generalized seizure. Results: A computed tomography scan of her head identified extensive CVT, located within the superior sagittal sinus and extending into the right transverse sinus. She remained biochemically hyperthyroid at the time of her presentation (thyroid-stimulating hormone = 0.10 mIU/L; free thyroxine = 32.8 pmol/L; free triiodothyronine = 10.0 pmol/L). A thrombotic workup revealed normal antithrombin, protein C, and ...
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