Abstract

Cerebral venous thrombosis (CVT) is occlusion of dural sinuses and/or cortical veins due to clot formation. It is a potentially life-threatening condition that requires rapid diagnosis and urgent treatment.Cerebral venous thrombosis is more common in females and young people. Pregnancy, postpartum state, contraceptive pills, infection, malignancy, hyper-coagulable state, rheumatological disorders, trauma are among the major etiologies of cerebral venous thrombosis. Headache, focal neurologic deficits and seizure were the most common clinical presentations. Different techniques of unenhanced and contrast enhanced brain computerized tomography(CT scan) and ,magnetic resonance imaging(MRI) are the most helpful ancillary investigations for diagnosis of Cerebral venous thrombosis.Specific treatment of the underlying cause of cerebral venous thrombosis should be considered as the mainstay of the treatment. Anticoagulation with heparin or low molecular weight heparinoids is the most accepted treatment. In acute phase, medical or surgical management to decrease intracranial pressure (ICP) is also recommended. If the patient's clinical condition aggravates despite adequate anticoagulation, thrombolysis or mechanical thrombectomy can be an additive option.

Highlights

  • Cerebral venous thrombosis (CVT) is a form of cerebrovascular disease primarily affecting cerebral venous sinuses

  • Authors concluded that patients with cerebral sinus thrombosis treated with anticoagulants had a favorable outcome more often than controls, but the difference was not statistically significant

  • The diameter of the cerebral dural sinuses are larger and venous thrombi are bigger [1]. intrasinus thrombolysis needs a considerable amount of time in comparison to intraarterial thrombolysis

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Summary

Introduction

Cerebral venous thrombosis (CVT) is a form of cerebrovascular disease primarily affecting cerebral venous sinuses. Superior sagittal sinus travels from anterior to posterior in a groove between falx cerebri and dura of inner table and terminates to torchular herophili (confluence of sinuses).Occipital sinus, located in the margin of falx cerebelli, run into confluence as well. It is absent in about of one third of persons. The venous blood drained from superior sagittal, occipital and straight sinuses goes into internal jugular vein through transverse and sigmoid sinuses. Inferior anastomotic vein of Labbe courses along the occipitotemporal sulcus and connects superior middle cerebral vein and the transverse sinus. A comprehensive list of established risk factors is provided in table 1

Pregnancy Puerperium
Clinical Manifestations
Laboratory Tests
Medical Treatment
Indications for Endovascular Treatment
Contraindication for Endovascular Intervention
Mechanical thrombectomy
Rheolytic thrombectomy
Manual Aspiration
Findings
Conclusion
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