Cerebral venous sinus thrombosis (CVST) an unusual presentation of COVID19- a case report from Bangladesh.

Abstract

Newly recognized pandemic infectious disease COVID19 (Corona-virus disease) is causes by severe acute respiratory syndrome corona-virus 2 (SARS-CoV-2). This viral infection causes hypercoagulability and inflammation leading to increase incidence of both arterial and venous thrombotic events (VTEs). Therefore patients infected with this novel virus seem to associated with higher risk of thrombotic events (TEs) resulting in thromembolic diseases, especially stroke and pulmonary embolism, or even cerebral venous sinus thrombosis (CVST). We report a case of 42-year-old female who presented with features of venous thrombotic events (extensive dural venous sinus thrombosis) and was subsequently found to have COVID-19 positive by reverse transcriptase-polymerase chain reaction (RT-PCR) test. The case report indicates CVST might be an unusual manifestation of COVID-19. CVST even present as initial symptoms of COV ID-19 without significant respiratory symptoms. Early diagnosis and treatment with thrombolytic agent in case of SARS-CoV-2 infection resulting in reduced morbidity and mortality. we recommend further study to establish SARS-CoV-2 virus (the COVID-19 disease) as a known risk factor for CVST.