Abstract

Cerebral venous sinus thrombosis (CVST) is an uncommon disease entity. In contrast-enhanced computed tomography (CT) or magnetic resonance venography (MRV) images of the brain, CVST usually manifests as a filling defect of the dural venous sinuses. Brain parenchymal involvement in CVST can be ranged from parenchymal oedema to haemorrhagic infarctions. Though the most frequent cause of haemorrhagic infarction in brain is CVST, other rare causes such as cerebral venous outflow obstruction due to neck vein pathology have been reported. We report a rare case of haemorrhagic brain infarctions secondary to bilateral internal jugular vein thrombosis in a 17-year-old woman, who has presented with worsening headache and seizures. She had high susceptibility of getting venous thrombosis for being a young female on oral contraceptive pills. While reporting a rare cause of cerebral haemorrhagic infarctions, this case report highlights the need for having a high degree of suspicion to diagnose CVST. Further, this case report emphasises the value of prompt and adequate imaging of neck veins if the haemorrhagic infarction presents with patent cerebral venous sinuses.

Highlights

  • Cerebral venous sinus thrombosis (CVST) is an uncommon disease, annually affects nearly 5 per million adults, accounts for 5% of young strokes, and shows female predominance

  • Magnetic resonance venography (MRV) is as sensitive as computed tomography (CT) venography in detecting CVST, in which CVST again manifests as a filling defect in venous sinus. ough the brain parenchymal involvement is not an essential feature of CVST, if present, brain involvement can be ranged from parenchymal oedema to haemorrhagic infarctions

  • Pathophysiology of brain parenchymal involvement is explained by poor venous drainage and associated high venous pressure that leads to poor arterial perfusion [2]. ough the most prevalent cause of poor venous drainage in haemorrhagic cerebral infarction is CVST, other rare causes have been reported [2]

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Summary

Introduction

Cerebral venous sinus thrombosis (CVST) is an uncommon disease, annually affects nearly 5 per million adults, accounts for 5% of young strokes, and shows female predominance. A vague presentation of CVST warrants a high degree of suspicion to diagnose early [1]. E CVST manifests as a filling defect of cerebral veins in contrast-enhanced computed tomography (CT) images. Magnetic resonance venography (MRV) is as sensitive as CT venography in detecting CVST, in which CVST again manifests as a filling defect in venous sinus. Ough the brain parenchymal involvement is not an essential feature of CVST, if present, brain involvement can be ranged from parenchymal oedema to haemorrhagic infarctions. Ough the most prevalent cause of poor venous drainage in haemorrhagic cerebral infarction is CVST, other rare causes have been reported [2]. We report a rare case of bilateral internal jugular vein thrombosis as the cause of poor venous drainage that leads to cerebral haemorrhagic infarctions

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