Abstract
Eighty-four patients with moyamoya disease, including 36 pediatric cases and 48 adult cases, were treated by revascularization surgery. Ischemic onset is a good indication for surgical revascularization in both pediatric and adult cases. Combined surgery of superficial temporal artery-middle cerebral artery anastomosis and indirect revascularization of encephalo-duro-arterio-myo-synangiosis (EDAMS) or encephalo-duro-myo-arterio-pericranio-synangiosis (EDAMPS), which is a minor modification of EDAMS, was performed. Ischemic attacks disappeared in most patients within 1 year (mean) after surgery. However, in adult cases with hemorrhagic onset, rebleeding was seen in 6 of 48 cases (12.5%; mean follow-up, 6 years). Recent advances in clinical and basic studies of moyamoya disease are reviewed.
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