Abstract
Cerebral metastases from ovarian/fallopian tube carcinoma, rare and highly dismal events, develop usually in patients with prolonged survival. There are only several reports on cancers in which brain involvements are present before or at the time of diagnosis of primary ovarian/fallopian tube carcinoma...
Highlights
Recent knowledge on histopathology and genetics have induced a paradigm shift that peritoneal, ovarian and fallopian tube carcinomas are considered as a spectrum of disease originating from the Müllerian duct remnant [1,2]
Consideration of the brain as a potential site of metastasis even early in the primary lesion may lead us to consider the occult ovarian/fallopian tube carcinoma in females affected by brain involvements
Central nervous system involvement occurs as a late manifestation of the disease developing after the initial diagnosis of primary tumor; less than 5 % are of the carcinoma [4,5,6]
Summary
Recent knowledge on histopathology and genetics have induced a paradigm shift that peritoneal, ovarian and fallopian tube carcinomas are considered as a spectrum of disease originating from the Müllerian duct remnant [1,2]. Cerebral metastases from ovarian/fallopian tube carcinoma, rare and highly dismal events, develop usually in patients with prolonged survival. There are only several reports on cancers in which brain involvements are present before or at the time of diagnosis of primary ovarian/fallopian tube carcinoma. We attempted to systemically review available evidence on brain metastasis as a first manifestation of ovarian/fallopian tube carcinomas.
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