Abstract

An 8-year-old boy presented with a rare cerebral medulloepithelioma manifesting as headache, nausea, and vomiting. Neuroimaging demonstrated a mass containing a cyst in the left frontal lobe. Gross total resection of the tumor with a 1-cm margin was performed under intraoperative monitoring. The histological diagnosis was medulloepithelioma. Stereotactic radiotherapy (total dose 20 Gy) was given to the brain up to 1 cm from the surgical margin. Follow-up neuroimaging 5 years later showed no signs of recurrence. He now attends junior high school, with normal mental and physiological development. Medulloepitheliomas are rare, highly malignant embryonal tumors of the central nervous system. Combined gross total tumor resection and radiotherapy are recommended to obtain the most favorable outcome.

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